The largest Mississippian ceremonial center known today is Cahokia. Located just outside St. Louis, Missouri, this city had a population of 10,000 to 20,000 people, contained nearly 200 earthen mounds, and covered five square miles.
Located on the banks of the Black Warrior River thirteen miles south of Tuscaloosa, Alabama, Moundville was established around AD 1000 and rose in prominence to become one of the principal ceremonial centers in the Mississippian world.
Etowah was a large Mississippian center constructed about the same time as Cahokia and Moundville. It is in present-day Georgia and sits on the banks of the Etowah River in Bartow County, just south of Cartersville. Containing six mounds, it was the largest known ritual center in the region from AD 1000 to –1550.